Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-κβ
| dc.contributor.author | Ferruelo, Antonio | |
| dc.contributor.author | Las Heras Alonso, Marta Mireya | |
| dc.contributor.author | Redondo, Cristina | |
| dc.contributor.author | Fata Chillón, Fernando Ramón de | |
| dc.contributor.author | Romero Cagigal, Ignacio | |
| dc.contributor.author | Angulo Cuesta, Javier | |
| dc.date.accessioned | 2015-07-23T15:47:01Z | |
| dc.date.available | 2015-07-23T15:47:01Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | Mediterranean diet may play a role in the prevention of prostate cancer (PCa) development and progression. Cyclooxygenase-2 (COX-2) expression is associated with increased cellular proliferation, prevents apoptosis and favors tumor invasion. We intend to clarify whether resveratrol and other polyphenols effectively inhibit COX-2 activity and induce apoptosis in hormone-resistant PC-3 cell line. | spa |
| dc.description.filiation | UEM | spa |
| dc.description.impact | 1.022 JCR (2014) Q4, 60/76 Urology & nephrology | spa |
| dc.identifier.citation | Ferruelo, A., de Las Heras, M. M., Redondo, C., de Fata, F. R., Romero, I., & Angulo, J. C. (2014). Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-κβ. Actas Urológicas Españolas (English Edition), 38(7), 429-437. | spa |
| dc.identifier.doi | 10.1016/j.acuroe.2014.06.004 | |
| dc.identifier.issn | 02104806 | |
| dc.identifier.issn | 16797980 | |
| dc.identifier.uri | http://hdl.handle.net/11268/4235 | |
| dc.language.iso | eng | spa |
| dc.peerreviewed | Si | spa |
| dc.rights.accessRights | restricted access | spa |
| dc.subject.other | Cáncer de próstata resistente a castración | spa |
| dc.subject.other | Línea celular PC-3 | spa |
| dc.subject.uem | Urologia | spa |
| dc.subject.unesco | Cáncer | spa |
| dc.title | Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-κβ | spa |
| dc.title.alternative | Los polifenoles del vino ejercen su efecto antineoplásico sobre la línea celular PC-3 andrógeno resistente a través de la inhibición de la actividad transcripcional del promotor de COX-2 mediada por NF-κβ | spa |
| dc.type | journal article | spa |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 86fca15d-84c1-443e-9d84-f791a5e1e056 | |
| relation.isAuthorOfPublication | eaadbb3a-67c4-43f5-b477-5fb2318b809a | |
| relation.isAuthorOfPublication.latestForDiscovery | 86fca15d-84c1-443e-9d84-f791a5e1e056 |