A Paradox: α-Klotho Levels and Smoking Intensity
| dc.contributor.author | Verde Rello, Zoraida | |
| dc.contributor.author | Gonzalez-Moro, Jose Miguel | |
| dc.contributor.author | Chicharro García, Luis Miguel | |
| dc.contributor.author | Reinoso Barbero, Luis | |
| dc.contributor.author | Bandrés Moya, Fernando | |
| dc.contributor.author | Gómez Gallego, Félix | |
| dc.contributor.author | Santiago Dorrego, Catalina | |
| dc.date.accessioned | 2016-10-30T19:11:28Z | |
| dc.date.available | 2016-10-30T19:11:28Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Reports regarding smoking differences in aklotho expression have provided conflicting results. In the current study we focused on the influence of smoking intensity to serum levels of the aging molecule a-klotho in healthy smokers. 40 middle aged healthy smokers without airway obstruction or restriction were selected for the analysis. Serum levels of soluble a-klotho were significantly higher in heavy smokers (P\0.001). These results are in agreement with the possibility that a-klotho acts as anti-inflammatory molecule and strengthen the hypothesis that an increase of serum levels of a-klotho might be a compensatory response to smoking stress in healthy population. | spa |
| dc.description.filiation | UEM | spa |
| dc.description.impact | 2.101 JCR (2017) Q3, 40/59 Respiratory System | spa |
| dc.description.sponsorship | NEUMOMADRID (2015) | spa |
| dc.identifier.citation | Verde, Z., González-Moro, J. M. R., Chicharro, L. M., Reinoso-Barbero, L., Bandrés, F., Gómez-Gallego, F., & Santiago, C. (2017). A Paradox: α-Klotho Levels and Smoking Intensity. Lung, 195(1), 53-57. DOI: 10.1007/s00408-016-9944-6 | spa |
| dc.identifier.doi | 10.1007/s00408-016-9944-6 | |
| dc.identifier.issn | 0341-2040 | |
| dc.identifier.uri | http://hdl.handle.net/11268/5937 | |
| dc.language.iso | eng | spa |
| dc.peerreviewed | Si | spa |
| dc.rights.accessRights | restricted access | spa |
| dc.subject.uem | Médicina | spa |
| dc.subject.unesco | Ciencias médicas | spa |
| dc.title | A Paradox: α-Klotho Levels and Smoking Intensity | spa |
| dc.type | journal article | spa |
| dspace.entity.type | Publication | |
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