Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice

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dc.contributor.authorMartín Alonso, M.
dc.contributor.authorGarcía Redondo, A. B.
dc.contributor.authorGuo, D.
dc.contributor.authorCamafeita, Emilio
dc.contributor.authorMartínez, Fernando
dc.contributor.authorAlfranca, A.
dc.contributor.authorMéndez Barbero, N.
dc.contributor.authorPollán, Á.
dc.contributor.authorSánchez-Camacho Blázquez, Cristina
dc.contributor.authorDenhardt, D. T.
dc.contributor.authorSeiki, Motoharu
dc.contributor.authorVázquez, J.
dc.contributor.authorSalaices, M.
dc.contributor.authorRedondo, J. M.
dc.contributor.authorMilewicz, D.
dc.contributor.authorArroyo, Alicia G.
dc.date.accessioned2015-11-12T15:21:28Z
dc.date.available2015-11-12T15:21:28Z
dc.date.issued2015
dc.description.abstractAortic dissection or rupture resulting from aneurysm causes 1% to 2% of deaths in developed countries. These disorders are associated with mutations in genes that affect vascular smooth muscle cell differentiation and contractility or extracellular matrix composition and assembly. However, as many as 75% of patients with a family history of aortic aneurysms do not have an identified genetic syndrome.spa
dc.description.filiationUEMspa
dc.description.impact11.551 JCR (2015) Q1, 4/124 Cardiac & cardiovascular systems, 3/70 Hematology, 2/63 Peripheral vascular diseasespa
dc.description.sponsorshipPlan Nacional I+Dspa
dc.identifier.citationMartín-Alonso, M., García-Redondo, A. B., Guo, D., Camafeita, E., Martínez, F., Alfranca, A., ... & Arroyo, A. G. (2015). Deficiency of MMP17/MT4-MMP Proteolytic Activity Predisposes to Aortic Aneurysm in Mice. Circulation research, 117(2), e13-26.spa
dc.identifier.doi10.1161/CIRCRESAHA.117.305108
dc.identifier.issn00097330
dc.identifier.issn15244571
dc.identifier.urihttp://hdl.handle.net/11268/4565
dc.language.isoengspa
dc.peerreviewedSispa
dc.rights.accessRightsrestricted accessspa
dc.subject.uemCardiologíaspa
dc.subject.unescoSaludspa
dc.subject.unescoSistema cardiovascularspa
dc.titleDeficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in micespa
dc.typejournal articlespa
dspace.entity.typePublication
relation.isAuthorOfPublicationa44736e3-73ca-4c03-96da-b1cc61ae3404
relation.isAuthorOfPublication.latestForDiscoverya44736e3-73ca-4c03-96da-b1cc61ae3404

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