Functional and Therapeutic Roles of Plant-Derived Antioxidants in Type 2 Diabetes Mellitus: Mechanisms, Challenges, and Considerations for Special Populations

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dc.contributor.authorClemente Suárez, Vicente Javier
dc.contributor.authorMartín Rodríguez, Alexandra
dc.contributor.authorBeltrán Velasco, Ana Isabel
dc.contributor.authorRubio Zarapuz, Alejandro
dc.contributor.authorMartínez Guardado, Ismael
dc.contributor.authorValcárcel Martín, Roberto
dc.contributor.authorTornero Aguilera, José Francisco
dc.date.accessioned2026-07-23T12:12:53Z
dc.date.available2026-07-23T12:12:53Z
dc.date.issued2025
dc.description.abstractType 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, oxidative stress, and inflammation, contributing to insulin resistance and long-term complications. Dietary antioxidants from plant sources, such as polyphenols, flavonoids, carotenoids, and phenolic acids, have been increasingly studied for their potential to modulate these pathophysiological mechanisms. This review aims to summarize and critically analyze the current evidence on the biological effects, therapeutic potential, and translational challenges of plant-derived antioxidants in the prevention and management of T2DM.en
dc.description.filiationUEMspa
dc.description.impact8.2 Q1 JCR 2025
dc.description.impact1.706 Q1 SJR 2025
dc.description.impactNo data IDR 2024
dc.description.sponsorshipSin financiaciónes
dc.identifier.citationClemente-Suárez, V. J., Martín-Rodríguez, A., Beltrán-Velasco, A. I., Rubio-Zarapuz, A., Martínez-Guardado, I., Valcárcel-Martín, R., & Tornero-Aguilera, J. F. (2025). Functional and therapeutic roles of plant-derived antioxidants in type 2 diabetes mellitus: Mechanisms, challenges, and considerations for special populations. Antioxidants, 14(6), 725. https://doi.org/10.3390/antiox14060725
dc.identifier.doi10.3390/antiox14060725
dc.identifier.issn2076-3921
dc.identifier.urihttps://hdl.handle.net/11268/17310
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.3390/antiox14060725
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.otherDiabetes mellitus tipo 2
dc.subject.otherAntioxidantes
dc.subject.otherEstrés oxidativo
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.unescoLucha contra las enfermedades
dc.subject.unescoInvestigación médica
dc.subject.unescoMedicina preventiva
dc.titleFunctional and Therapeutic Roles of Plant-Derived Antioxidants in Type 2 Diabetes Mellitus: Mechanisms, Challenges, and Considerations for Special Populations
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublicationa2e25626-16b1-41bc-9c67-8de8ce6e007d
relation.isAuthorOfPublication.latestForDiscoverya2e25626-16b1-41bc-9c67-8de8ce6e007d

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