‘Mitotherapy’ for heart failure

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Sanchís-Gomar, Fabián
Lippi, Giuseppe

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Abnormalities in mitochondrial dynamics along with those for the molecular mediators involved are presently being viewed with increased interest in the field of cardiovascular disease. Recent research highlights OPA1, a dynamin-like GTPase mediating mitochondrial fusion, as well as the 'mitoproteases' OMA1 and YME1L, as potential therapeutic targets against heart failure.

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Sanchis-Gomar, F., Lippi, G., & Lucia, A. (2016). ‘Mitotherapy’ for heart failure. Trends in molecular medicine, 22(4), 267-269.

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