The ‘autoimmunome’ of centenarians

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dc.contributor.authorCarrera Bastos, Pedro
dc.contributor.authorPlaza Florido, Abel
dc.contributor.authorSantos Lozano, Alejandro
dc.contributor.authorBorba, Vania
dc.contributor.authorRodríguez Romo, Gabriel
dc.contributor.authorGarcía Chico, Celia
dc.contributor.authorSaco Ledo, Gonzalo
dc.contributor.authorEmanuele, Enzo
dc.contributor.authorShoenfeld, Yehuda
dc.contributor.authorLucía Mulas, Alejandro
dc.date.accessioned2026-07-29T14:56:27Z
dc.date.available2026-07-29T14:56:27Z
dc.date.issued2025
dc.description.abstractThe objective is to identify signature proteins potentially linked to resistance to autoimmunity in the blood of centenarians. Elevated albumin levels and a prominent complement system presence in centenarians’ blood proteome may contribute to resistance to autoimmunity, highlighting potential protective mechanisms against autoimmune diseases in extreme longevity.en
dc.description.filiationUEMspa
dc.description.impact3.8 Q2 JCR 2025
dc.description.impact1.172 Q2 SJR 2025
dc.description.impactNo data IDR 2024
dc.description.sponsorshipApoyo de investigación del World Cancer Research Fund y la Universidad Europea Miguel de Cervantes recibido por Alejandro Lucia y Celia Garcia-Chico, respectivamente. Los autores declaran que dicho apoyo no influyó en el diseño, análisis ni interpretación del estudio actual.es
dc.identifier.citationCarrera-Bastos, P., Plaza-Florido, A., Santos-Lozano, A., Borba, V., Rodríguez-Romo, G., García-Chico, C., Lista, S., Saco-Ledo, G., Emanuele, E., Shoenfeld, Y., & Lucia, A. (2025). The ‘autoimmunome’ of centenarians. Journal of Translational Autoimmunity, 11, 100295. https://doi.org/10.1016/j.jtauto.2025.100295
dc.identifier.doi10.1016/J.JTAUTO.2025.100295
dc.identifier.issn2589-9090
dc.identifier.urihttps://hdl.handle.net/11268/17332
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.1016/J.JTAUTO.2025.100295
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.otherCiencias del Deporte
dc.subject.otherAutoinmunidad
dc.subject.otherAlbúmina Sérica
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.sdgGoal 9: Build resilient infrastructure, promote sustainable industrialization and foster innovation
dc.subject.unescoCiencias médicas
dc.subject.unescoInmunología
dc.subject.unescoGerontología
dc.titleThe ‘autoimmunome’ of centenariansen
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublication3b862233-e100-422b-b12f-f1e94212b33c
relation.isAuthorOfPublicationd3691359-d7bd-4a12-b84e-338e28c81f9f
relation.isAuthorOfPublication.latestForDiscovery3b862233-e100-422b-b12f-f1e94212b33c

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