The ‘autoimmunome’ of centenarians

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URI: https://hdl.handle.net/11268/17332
DOI: 10.1016/J.JTAUTO.2025.100295

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2025

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Carrera Bastos, Pedro
Plaza Florido, Abel
Santos Lozano, Alejandro
Borba, Vania

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goal-9

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The objective is to identify signature proteins potentially linked to resistance to autoimmunity in the blood of centenarians. Elevated albumin levels and a prominent complement system presence in centenarians’ blood proteome may contribute to resistance to autoimmunity, highlighting potential protective mechanisms against autoimmune diseases in extreme longevity.

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Ciencias médicas
Inmunología
Gerontología

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Carrera-Bastos, P., Plaza-Florido, A., Santos-Lozano, A., Borba, V., Rodríguez-Romo, G., García-Chico, C., Lista, S., Saco-Ledo, G., Emanuele, E., Shoenfeld, Y., & Lucia, A. (2025). The ‘autoimmunome’ of centenarians. Journal of Translational Autoimmunity, 11, 100295. https://doi.org/10.1016/j.jtauto.2025.100295
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https://doi.org/10.1016/J.JTAUTO.2025.100295

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Área de Ciencias de la Salud
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