Proteomics signatures of human breast cancer: A systematic review

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dc.contributor.authorGarcía Chico, Celia
dc.contributor.authorPlaza Florido, Abel
dc.contributor.authorLópez Ortiz, Susana
dc.contributor.authorPinto Fraga, José
dc.contributor.authorMaroto Izquierdo, Sergio
dc.contributor.authorKhoramipour, Kayvan
dc.contributor.authorSagarra Romero, Lucía
dc.contributor.authorFiuza Luces, María del Carmen
dc.contributor.authorLucía Mulas, Alejandro
dc.contributor.authorSantos Lozano, Alejandro
dc.date.accessioned2026-07-31T12:40:38Z
dc.date.available2026-07-31T12:40:38Z
dc.date.issued2025
dc.description.abstractProteomics can play an important role in advancing the discovery of cancer biomarkers. We aimed to synthesize current evidence concerning proteome signatures and molecular pathways involved in human breast cancer (BC). Our review provides a comprehensive overview of the proteomic profile of patients with BC and may contribute to the understanding of the molecular changes associated with this disease. We highlighted hundreds of proteins, and various molecular pathways involved in BC, which could be considered potential biomarkers involved in the pathophysiology of the disease. Our results may also pave the way for new avenues to explore treatment targets.en
dc.description.filiationUEMspa
dc.description.impact6.2 Q1 JCR 2025
dc.description.impact1.977 Q1 2025
dc.description.impactNo data IDR 2024
dc.description.sponsorshipVer financiación en https://doi.org/10.1016/J.CRITREVONC.2025.104950es
dc.identifier.citationGarcía-Chico, C., Plaza-Florido, A., López-Ortiz, S., Pinto-Fraga, J., Maroto-Izquierdo, S., Khoramipour, K., Sagarra-Romero, L., Fiuza-Luces, C., Lucia, A., & Santos-Lozano, A. (2025). Proteomics signatures of human breast cancer: A systematic review. Critical Reviews in Oncology/Hematology, 216, 104950. https://doi.org/10.1016/j.critrevonc.2025.104950
dc.identifier.doi10.1016/J.CRITREVONC.2025.104950
dc.identifier.issn1040-8428
dc.identifier.issn1879-0461
dc.identifier.urihttps://hdl.handle.net/11268/17348
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.1016/J.CRITREVONC.2025.104950
dc.rights.accessRightsembargoed access
dc.subject.otherCiencias del Deporte
dc.subject.otherNeoplasias de la Mama
dc.subject.otherProteómica
dc.subject.otherBiomarcadores Tumorales
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.sdgGoal 9: Build resilient infrastructure, promote sustainable industrialization and foster innovation
dc.subject.unescoCiencias médicas
dc.subject.unescoCáncer
dc.subject.unescoBioquímica
dc.titleProteomics signatures of human breast cancer: A systematic reviewen
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublication2f4b38cb-548f-485d-b44b-bd7851010b36
relation.isAuthorOfPublicationd3691359-d7bd-4a12-b84e-338e28c81f9f
relation.isAuthorOfPublication.latestForDiscovery2f4b38cb-548f-485d-b44b-bd7851010b36

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