Regenerative Peripheral Nerve Interface (RPNI) and vascularized Denervated Muscle Targets (VDMT): a preclinical rabbit model as a translational feasibility and methodological platform

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dc.contributor.authorGonzález Prieto, Jorge
dc.contributor.authorArenillas, Mario
dc.contributor.authorSanz Barbero, Elisa
dc.contributor.authorGutiérrez Pecharromán, Ana
dc.contributor.authorDaniel Muñoz, José
dc.contributor.authorAlonso, Eduardo
dc.contributor.authorMorillo, María del Carmen
dc.contributor.authorCristóbal, Lara
dc.contributor.authorMaldonado Morillo, Andrés
dc.date.accessioned2026-08-25T11:51:26Z
dc.date.available2026-08-25T11:51:26Z
dc.date.issued2026
dc.description.abstractRegenerative Peripheral Nerve Interfaces (RPNIs) and Vascularized Denervated Muscle Targets (VDMTs) are emerging strategies for nerve regeneration and myoelectric prosthesis control. Most preclinical studies have been conducted in rodents, limiting the evaluation of implantable electromyographic devices due to anatomical and scale-related constraints. This study aimed to develop and evaluate the first RPNI and VDMT models in rabbits as a translational platform for implantable neuromuscular interfaces.en
dc.description.filiationUEMspa
dc.description.impact9.7 Q1 JCR 2025
dc.description.impact2.407 Q1 SJR 2025
dc.description.impactNo data IDR 2024
dc.description.sponsorshipInstituto Carlos III (PI22/00862)es
dc.identifier.citationGonzález-Prieto, J., Arenillas, M., Sanz Barbero, E., Gutiérrez Pecharromán, A., Muñoz, J. D., Alonso, E., Morillo, M. D. C., Cristóbal, L., Giannetti, R., & Maldonado, A. A. (2026). Regenerative Peripheral Nerve Interface (Rpni) and vascularized Denervated Muscle Targets (Vdmt): A preclinical rabbit model as a translational feasibility and methodological platform. Journal of Translational Medicine, 24(1), 998. https://doi.org/10.1186/s12967-026-08453-y
dc.identifier.doi10.1186/s12967-026-08453-y
dc.identifier.issn1479-5876
dc.identifier.urihttps://hdl.handle.net/11268/17380
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.1186/s12967-026-08453-y
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.otherDepartamento clínico
dc.subject.otherNervios periféricos
dc.subject.otherRegeneración nerviosa
dc.subject.otherFenómenos fisiológicos del sistema nervioso
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.unescoSistema nervioso
dc.subject.unescoInvestigación médica
dc.subject.unescoMedicina preventiva
dc.titleRegenerative Peripheral Nerve Interface (RPNI) and vascularized Denervated Muscle Targets (VDMT): a preclinical rabbit model as a translational feasibility and methodological platform
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublicationba10d23a-0666-4193-986a-feccf14cbca9
relation.isAuthorOfPublicatione1163d4d-ad1e-403f-83a1-82ce74b604a3
relation.isAuthorOfPublication.latestForDiscoveryba10d23a-0666-4193-986a-feccf14cbca9

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