Therapeutic effect of cilastatin administration in LPS-induced retinotoxicity
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San Felipe Riba, Diego
Martín Sanchez, Beatriz
González Nicolás, María
Llorente Miguel, Ricardo
Marco López, Eva María
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Abstract
Sepsis is a life-threatening condition characterized by a dysregulated host response to infection that leads to multi-organ dysfunction. While its impact on the central nervous system is increasingly recognized, its effects on the retina require further study. Herein, this study aims to determine if systemic LPS‑induced sepsis causes retinal damage and whether cilastatin (CIL) may attenuate this injury.
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San Felipe, D., Martín-Sánchez, B., González-Nicolás, M. A., Llorente, R., Marco, E. M., López-Gallardo, M., & Lázaro, A. (2026). Therapeutic effect of cilastatin administration in LPS-induced retinotoxicity. Biomedicine & Pharmacotherapy, 200, 119557. https://doi.org/10.1016/j.biopha.2026.119557
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https://doi.org/10.1016/j.biopha.2026.119557Type of document
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