Disruption of CaV2.3 channels in the brain of the 5xFAD mice

Simple item page
dc.contributor.authorAguado, Carolina
dc.contributor.authorAlfaro Ruiz, Rocío
dc.contributor.authorMartín Belmonte, Alejandro
dc.contributor.authorPuertas Avendaño, Ricardo
dc.contributor.authorFernández, Miriam
dc.contributor.authorMartínez Poyato, María Llanos
dc.contributor.authorPortero Campillo, Eloy
dc.contributor.authorPozuelo Montero, Miguel
dc.contributor.authorMoreno Martínez, Ana Esther
dc.contributor.authorAlonso Gómez, Pablo
dc.contributor.authorEt. al.
dc.contributor.editorMasuo Ohno
dc.date.accessioned2025-11-28T11:50:35Z
dc.date.available2025-11-28T11:50:35Z
dc.date.issued2025-11-26
dc.description.abstractCaV2.3 (R-type) channels mediate calcium signals involved in neuronal excitability, synaptic plasticity, and neurotransmitter release in the hippocampus. However, there is currently no information about their potential changes in Alzheimer's disease (AD). This study aims to analyze the protein levels, expression, and subcellular localization of CaV2.3 channels in the hippocampus of 5xFAD mice. Methods.
dc.description.filiationUEV
dc.description.impact3.1 Q2 JCR 2024spa
dc.description.impact1.166 Q1 SJR 2024spa
dc.description.impactNo data IDR 2024spa
dc.description.sponsorshipPID2021-125875OB-I00
dc.description.sponsorshipPID2024-155887OB-I00
dc.description.sponsorshipOtra financiación : 10.1177/13872877251396963
dc.identifier.citationAguado, C., Alfaro-Ruiz, R., Martín-Belmonte, A., Puertas-Avendaño, R., Fernández, M., Martínez-Poyato, M. L., Portero-Campillo, E., Pozuelo-Montero, M., Moreno-Martínez, A. E., Alonso-Gómez, P., Kulik, A., & Luján, R. (2025). Disruption of CaV 2.3 channels in the brain of the 5xFAD mice. Journal of Alzheimer’s Disease, 13872877251396963. https://doi.org/10.1177/13872877251396963
dc.identifier.doi10.1177/13872877251396963
dc.identifier.issn1387-2877
dc.identifier.issn1875-8908
dc.identifier.urihttps://hdl.handle.net/11268/16532
dc.language.isoeng
dc.peerreviewedSi
dc.publisherSAGE Publications
dc.relation.publisherversionhttps://doi.org/10.1177/13872877251396963
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subject.otherBloqueadores del Canal de Sodio Activado por Voltaje
dc.subject.otherCerebro
dc.subject.otherHipocampo
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.unescoInvestigación médica
dc.subject.unescoInvestigación sobre el cerebro
dc.titleDisruption of CaV2.3 channels in the brain of the 5xFAD mice
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Disruption of CaV2.3 channels in the brain_2025.pdf
Size:
6.27 MB
Format:
Adobe Portable Document Format
Download

Collections

Área de Ciencias de la Salud