Disruption of CaV2.3 channels in the brain of the 5xFAD mice
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Aguado, Carolina
Alfaro Ruiz, Rocío
Martín Belmonte, Alejandro
Puertas Avendaño, Ricardo
Fernández, Miriam
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Masuo Ohno
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SAGE Publications
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Abstract
CaV2.3 (R-type) channels mediate calcium signals involved in neuronal excitability, synaptic plasticity, and neurotransmitter release in the hippocampus. However, there is currently no information about their potential changes in Alzheimer's disease (AD). This study aims to analyze the protein levels, expression, and subcellular localization of CaV2.3 channels in the hippocampus of 5xFAD mice.
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Bibliographic reference
Aguado, C., Alfaro-Ruiz, R., Martín-Belmonte, A., Puertas-Avendaño, R., Fernández, M., Martínez-Poyato, M. L., Portero-Campillo, E., Pozuelo-Montero, M., Moreno-Martínez, A. E., Alonso-Gómez, P., Kulik, A., & Luján, R. (2025). Disruption of CaV 2.3 channels in the brain of the 5xFAD mice. Journal of Alzheimer’s Disease, 13872877251396963. https://doi.org/10.1177/13872877251396963
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https://doi.org/10.1177/13872877251396963Type of document
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