Real-World Comparison of Balloon-Expandable Valves for Transcatheter Aortic Valve Replacement: Data From the AorticþMitral TRAansCatheter Valve Registry

Abstract

Background: Comparative real-world data on newer balloon-expandable valve (BEV) platforms remain limited. We sought to compare clinical, procedural, and early hemodynamic outcomes following transcatheter aortic valve replacement (TAVR) using 2 contemporary BEVs in a multicenter international registry. Methods: Consecutive patients undergoing TAVR with Sapien 3/Ultra and MyVal from the Aortic+Mitral TRAansCatheter Valve Registry were included. Propensity score matching was used to generate a balanced 1:3 cohort. The primary endpoint was 2-year all-cause mortality. Secondary endpoints included in-hospital complications, defined according to Valve Academic Research Consortium–3 criteria.