Real-World Comparison of Balloon-Expandable Valves for Transcatheter Aortic Valve Replacement: Data From the AorticþMitral TRAansCatheter Valve Registry
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Talmor Barkan, Yeela
Patel, Kush P.
Barbanti, Marco
Sammartino, Sofia
Costa, Giuliano
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Background: Comparative real-world data on newer balloon-expandable valve (BEV) platforms remain limited. We sought to compare clinical, procedural, and early hemodynamic outcomes following transcatheter aortic valve replacement (TAVR) using 2 contemporary BEVs in a multicenter international registry. Methods: Consecutive patients undergoing TAVR with Sapien 3/Ultra and MyVal from the Aortic+Mitral TRAansCatheter Valve Registry were included. Propensity score matching was used to generate a balanced 1:3 cohort. The primary endpoint was 2-year all-cause mortality. Secondary endpoints included in-hospital complications, defined according to Valve Academic Research Consortium–3 criteria.
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Talmor-Barkan, Y., Patel, K. P., Barbanti, M., Sammartino, S., Costa, G., Grasso, C., De Backer, O., Lulic, D., Olmos, C., Masiero, G., Adamo, M., Arzamendi, D., García-Gómez, M., Baz, J. A., Steblovnik, K., Mauri, V., Adam, M., Wienemann, H., Hein, M., … Witberg, G. (2026). Real-world comparison of balloon-expandable valves for transcatheter aortic valve replacement: Data from the aortic+mitral traanscatheter valve registry. Structural Heart, 10(10), 101104. https://doi.org/10.1016/j.shj.2026.101104