Acute toxicity of SBRT in localized prostate cancer: A Spanish multicenter study

dc.contributor.authorRomero Zoghbi, S. E.
dc.contributor.authorLópez Campos, Fernando
dc.contributor.authorSanz Rosa, David
dc.contributor.authorFernández Ibiza, Jaime
dc.contributor.authorThuissard Vasallo, Israel John
dc.contributor.authorAndreu Vázquez, Cristina
dc.contributor.authorLaria, C.
dc.contributor.authorOcanto, Abrahams
dc.contributor.authorGonsalves, Daniela
dc.contributor.authorCouñago Lorenzo, Felipe
dc.contributor.authorEt. al.
dc.date.accessioned2025-12-09T17:56:13Z
dc.date.available2025-12-09T17:56:13Z
dc.date.issued2025
dc.description.abstractStereotactic body radiation therapy (SBRT) has emerged as an effective option for the treatment of localized prostate cancer; however, data from real-world clinical practice remain limited. Between January 2020 and December 2023, 251 patients with localized prostate cancer treated with SBRT were included in 12 centers in Spain. The treatment volume included prostate ± seminal vesicles, without prophylactic pelvic radiotherapy. A dose of 35−40 Gy was prescribed in 5 fractions, every other day. Acute genitourinary (GU), gastrointestinal (GI) and sexual toxicity was assessed up to 6 months post-treatment using the Common Terminology Criteria for Adverse Events (CTCAE) v5.0. The aim purpose of this study is to evaluate the safeness of the Five-fraction SBRT treatment.
dc.description.filiationUEMspa
dc.description.impactNo data 2024spa
dc.description.sponsorshipSin financiación
dc.identifier.citationRomero Zoghbi, S. E., López Campos, F., Sanz-Rosa, D., Fernández Ibiza, J., Thuissard-Vasallo, I. J., Andreu-Vázquez, C., Laria, C., Andreescu Yagüe, J., Krumina, E., Ocanto, A., Mateos, M., Glaría, L. A., García Cuesta, J. A., Gonsalves, D., Fernández, C., Esteban, D., Begara De La Fuente, J., Rivas, D., López Ramírez, E., … Couñago, F. (2025). Acute toxicity of SBRT in localized prostate cancer: A Spanish multicenter study. Actas Urológicas Españolas (English Edition), 49(8), 501798. https://doi.org/10.1016/j.acuroe.2025.501798
dc.identifier.doi10.1016/j.acuroe.2025.501798
dc.identifier.issn2173-5786
dc.identifier.urihttps://hdl.handle.net/11268/16588
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.1016/j.acuroe.2025.501798
dc.rights.accessRightsembargoed access
dc.subject.otherNeoplasias de la próstata
dc.subject.otherPruebas de toxicidad
dc.subject.otherProtocolos antineoplásicos
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.unescoInvestigación médica
dc.subject.unescoCáncer
dc.subject.unescoTratamiento médico
dc.titleAcute toxicity of SBRT in localized prostate cancer: A Spanish multicenter study
dc.title.alternativeToxicidad aguda de la SBRT en cáncer de próstata localizado: estudio multicéntrico español
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
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relation.isAuthorOfPublication6ec266f2-8e29-4c5c-be70-5f0a58f67db8
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relation.isAuthorOfPublication.latestForDiscovery9d1f9950-077f-4566-9a9d-b15d6c626060

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