Aceite de coco: tratamiento alternativo no farmacológico frente a la enfermedad de Alzheimer
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Hu Yang, Iván
Rubia Ortí, José Enrique de la
Selvi Sabater, Pablo
Sancho Castillo, Sandra
Rochina, Mariano Julián
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Abstract
Introducción: la enfermedad de Alzheimer es la demencia
más prevalente en la actualidad. En cuanto al
tratamiento, no existe cura farmacológica definitiva, con
lo cual son necesarias nuevas alternativas terapéuticas.
En este sentido, los triglicéridos de cadena media suponen
una fuente directa de energía celular y pueden ser
una alternativa no farmacológica a la muerte neuronal
por falta de la misma, que se produce en los enfermos de
Alzheimer.
Objetivo: evaluar el impacto que tiene el aceite de coco
en la evolución de la demencia tipo Alzheimer, en cualquier
grado de demencia. Asimismo, determinar si existe
influencia en dicha mejora, de variables como el sexo y
padecer o no diabetes mellitus tipo II.
Material y métodos: estudio prospectivo realizado en
pacientes con demencia tipo Alzheimer, con un grupo
control y un grupo de intervención al que se le administró
40 ml/día de aceite de coco virgen extra. Los parámetros
evaluados han sido las puntuaciones del test del miniexamen
cognoscitivo de Lobo, pre y postintervención en ambos
grupos.
Resultados: se observó en los sujetos que tomaban el
producto un aumento estadísticamente significativo de la
puntuación del test MEC-LOBO y, por consiguiente, una
mejoría del estado cognitivo, mejorando sobre todo las
mujeres, los que no tenían diabetes mellitus tipo II y los
pacientes graves.
Conclusión: este estudio, aunque preliminar, demuestra
la influencia positiva del aceite de coco a nivel cognitivo
en los pacientes con Alzheimer, siendo esta mejoría
dependiente del sexo, de la existencia o no de diabetes y
del grado de demencia.
Background: Alzheimer’s dementia is the most prevalent nowadays. As for treatment, there is no definitive cure drug, thus new therapies are needed. In this regard the medium chain triglycerides are a direct source of cellular energy and can be a nonpharmacological alternative to the neuronal death for lack of it, that occurs in Alzheimer patients. Objective: to evaluate the impact of coconut oil in the development of Alzheimer’s dementia, in any degree of dementia. Also determine whether this improvement influences within variables such as sex and suffering or not Type II Diabetes Mellitus. Material and methods: a prospective study was conducted in patients with Alzheimer’s dementia, with a control and an intervention group which was administered 40 ml/day of extra virgin coconut oil. The parameters evaluated were the mini test scores Lobo cognitive test, pre and post intervention in both groups. Results: it was observed in subjects taking the product, a statistically significant increase in test score MECWOLF and therefore an improvement in cognitive status, improving especially women’s, those without diabetes mellitus type II, and severe patients. Conclusion: this study, although preliminary, demonstrated the positive influence of coconut oil at the cognitive level of patients with Alzheimer’s, this improvement being dependent on sex, presence or absence of diabetes and degree of dementia.
Background: Alzheimer’s dementia is the most prevalent nowadays. As for treatment, there is no definitive cure drug, thus new therapies are needed. In this regard the medium chain triglycerides are a direct source of cellular energy and can be a nonpharmacological alternative to the neuronal death for lack of it, that occurs in Alzheimer patients. Objective: to evaluate the impact of coconut oil in the development of Alzheimer’s dementia, in any degree of dementia. Also determine whether this improvement influences within variables such as sex and suffering or not Type II Diabetes Mellitus. Material and methods: a prospective study was conducted in patients with Alzheimer’s dementia, with a control and an intervention group which was administered 40 ml/day of extra virgin coconut oil. The parameters evaluated were the mini test scores Lobo cognitive test, pre and post intervention in both groups. Results: it was observed in subjects taking the product, a statistically significant increase in test score MECWOLF and therefore an improvement in cognitive status, improving especially women’s, those without diabetes mellitus type II, and severe patients. Conclusion: this study, although preliminary, demonstrated the positive influence of coconut oil at the cognitive level of patients with Alzheimer’s, this improvement being dependent on sex, presence or absence of diabetes and degree of dementia.
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Hu Yang, I., Rubia Ortí, J. E., Selvi Sabater, P., Sancho Castillo, S., Rochina, M. J., Manresa Ramón, N., y Montoya Castilla, I. (2015). Aceite de coco: tratamiento alternativo no farmacológico frente a la enfermedad de Alzheimer. Nutrición hospitalaria, 32(6), 2822-2827. http://dx.doi.org/ 10.3305/nh.2015.32.6.9707


