Energy-Efficient Ultrasound-Assisted Extraction of Phenolic Compounds from Orange Peel Using COSMO-RS-Guided Selection of NADES

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URI: https://hdl.handle.net/11268/17134
DOI: 10.1007/s12161-026-03141-5

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2026

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Gómez Urios, Clara
Cortés Fenollar, Clara
López Malo, Daniel
Esteve Mas, María José
Blesa Jarque, Jesús

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goal-3
goal-12

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Abstract

Orange peel (OP) is a relevant by-product of the citrus industry, rich in phenolic compounds and ascorbic acid (AA), but its sustainable valorization requires green and efficient extraction strategies. In this study, six natural deep eutectic solvents (NADES) selected via COSMOTherm solubility modelling were evaluated for the recovery of bioactive compounds from OP using ultrasound-assisted extraction (UAE) followed by a stirring treatment. Overall, the study demonstrates that tailored NADES–UAE combinations constitute an effective and sustainable approach for recovering high-value antioxidants from orange peel, contributing to circular economy strategies and green extraction technologies.

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Ciencias médicas
Nutrición
Tecnología alimentaria

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Gomez-Urios, C., Cortés, C., Lopez-Malo, D., Esteve, M. J., & Blesa, J. (2026). Energy-Efficient Ultrasound-Assisted Extraction of Phenolic Compounds from Orange Peel Using COSMO-RS-Guided Selection of NADES. Food Analytical Methods, 19(8), 229.
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https://doi.org/10.1007/s12161-026-03141-5

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journal article

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Área de Ciencias de la Salud
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