A DNA hypermethylation profile reveals new potential biomarkers for prostate cancer diagnosis and prognosis

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URI: http://hdl.handle.net/11268/4230
DOI: 10.1002/pros.22833

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2014

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Ashour, Nadia
Andrés, Guillermo
Alelú, Raúl
González-Corpas, Ana

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DNA hypermethylation has emerged as a novel molecular biomarker for the evaluation of prostate cancer diagnosis and prognosis. Defining the specific gene hypermethylation profile for prostate cancer could involve groups of genes that specifically discriminate patients with indolent and aggressive tumors. Genome-wide methylation analysis was performed on 83 tumor and 10 normal prostate samples using the GoldenGate Methylation Cancer Panel I (Illumina, Inc.). All clinical stages of disease were considered.

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Cáncer

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Ashour, N., Angulo, J. C., Andrés, G., Alelú, R., González‐Corpas, A., Toledo, M. V., ... & Ropero, S. (2014). A DNA hypermethylation profile reveals new potential biomarkers for prostate cancer diagnosis and prognosis. The Prostate, 74(12), 1171-1182.

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journal article

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Otras Áreas de Investigación de Salud