Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study

Simple item page
dc.contributor.authorMarty, F. M.
dc.contributor.authorMan, C. Y.
dc.contributor.authorVan der Horst, C.
dc.contributor.authorFrancois, B.
dc.contributor.authorGarot, D.
dc.contributor.authorMánez, R.
dc.contributor.authorThamlikitkul, V.
dc.contributor.authorLorente Balanza, José Ángel
dc.contributor.authorÁlvarez Lerma, Francisco
dc.contributor.authorBrealey, D.
dc.contributor.authorZhao, H. H.
dc.contributor.authorWeller, S.
dc.contributor.authorYates, P. J.
dc.contributor.authorPeppercorn, A. F.
dc.date.accessioned2015-07-17T16:55:41Z
dc.date.available2015-07-17T16:55:41Z
dc.date.issued2014
dc.description.abstractIntravenous zanamivir is a neuraminidase inhibitor suitable for treatment of hospitalized patients with severe influenza. Patients were treated with intravenous zanamivir 600 mg twice daily, adjusted for renal impairment, for up to 10 days. Primary outcomes included adverse events (AEs), and clinical/laboratory parameters. Pharmacokinetics, viral load, and disease course were also assessed.spa
dc.description.filiationUEMspa
dc.description.impact5.997 JCR (2014) Q1, 18/148 Inmunology, 4/78 Infectious diseases, 14/119 Microbiologyspa
dc.identifier.citationMarty, F. M., Man, C. Y., van der Horst, C., Francois, B., Garot, D., Máňez, R., ... & Peppercorn, A. F. (2014). Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study. Journal of Infectious Diseases, 209(4), 542-50.spa
dc.identifier.doi10.1093/infdis/jit467
dc.identifier.issn00221899
dc.identifier.issn15376613
dc.identifier.urihttp://hdl.handle.net/11268/4210
dc.language.isospaspa
dc.peerreviewedSispa
dc.rights.accessRightsopen accessspa
dc.subject.otherZanamivirspa
dc.subject.uemMedicamentosspa
dc.subject.unescoInvestigación médicaspa
dc.titleSafety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II studyspa
dc.typejournal articlespa
dspace.entity.typePublication
relation.isAuthorOfPublication91e712d1-cbf0-4eab-9536-461d26ddbddf
relation.isAuthorOfPublication.latestForDiscovery91e712d1-cbf0-4eab-9536-461d26ddbddf

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
LorenteBalanza20150715.pdf
Size:
568.13 KB
Format:
Adobe Portable Document Format
Description:
Download

Collections

Otras Áreas de Investigación de Salud