Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave

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URI: http://hdl.handle.net/11268/13388
DOI: 10.1186/s12877-024-05402-6

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2024

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Pérez, Patricia
García, Nuria
Ballesteros Sanabria, Laura
Martínez, Rosa María

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Abstract

The function of mucosal secretory IgA (SIgA) seems to be paramount in the immune response against SARS-CoV-2 however, there are few studies addressing this issue specifically in the institutionalized older population. This study aims to determine the levels of secretory IgA against the S1 domain of the SARS-CoV-2 spike (SIgA-S1) in older people living in nursing homes (NH) and to investigate the differences in baseline characteristics, severity of COVID-19, duration of symptoms, 30-day mortality, and reinfection according to the levels of SIgA-S1.

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Pandemia
Inmunología
Anciano

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Bielza, R., Pérez, P., García, N., Ballesteros-Sanabria, L., Martínez, R. M., Ghazi, A., Hernando, C., Rodríguez, M. V., Thuissard, I. J., Andreu-Vázquez, C., & Bautista, J. M. (2024). Unravelling the role of secretory Immnuoglobulin-A in COVID-19: A multicentre study in nursing homes during the first wave. BMC Geriatrics, 24(1), 804. https://doi.org/10.1186/s12877-024-05402-6
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https://doi.org/10.1186/s12877-024-05402-6

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journal article

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