Tumour SNPs Associated with Immune-Related Hepatitis in Patients with Melanoma Receiving Immune Checkpoint Inhibitors

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URI: https://hdl.handle.net/11268/17154
DOI: 10.3390/biomedicines13102351

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2025

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Rodríguez Piñas, José María

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SDG

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Abstract

Immune checkpoint inhibitors (ICIs) have significantly improved survival rates for patients with metastatic melanoma. However, these treatments can lead to immune-related adverse events (irAEs), including hepatitis. This exploratory study sought to identify tumour single-nucleotide polymorphisms (SNPs) associated with the risk of ICI-induced hepatitis in melanoma patients.

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Cáncer
Patología
Inmunología

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Rodríguez-Piñas, J. M., Romero-Lorca, A., Gaibar, M., Novillo, A., Rubio, M., Malón, D., Antón-Pascual, B., Camacho, F. I., Cavanagh, M., Luján, D. R., Martín, A. M., Khedaoui, R., Moreno, D., Pinedo, F., Boiza, M., García-Adrián, S., Gómez, P., Marrupe, D., & Fernández-Santander, A. (2025). Tumour snps associated with immune-related hepatitis in patients with melanoma receiving immune checkpoint inhibitors. Biomedicines, 13(10), 2351. https://doi.org/10.3390/biomedicines13102351
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https://doi.org/10.3390/biomedicines13102351

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journal article

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Área de Biomedicina Clásica
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