Resumen:
Due to the global concern over antimicrobial
resistance,
1 advanced materials are being studied
for their possible antimicrobial properties.
Nanoparticles (NPs) have been shown to have
antimicrobial effect against certain pathogens. In our
study, an initial antimicrobial screening of 13
different NPs standard materials against a series of
harmful micro-organisms was carried out. Along with
Copper (Cu) and Silver (Ag) NPs, certain Graphene
oxides NPs were found to effectively counteract a
fungal species, called Candida albicans.
2 With an
aim to improve colloidal stabilities of this Graphene
oxides (GO), hence to provide better opportunities to
microbial exposure, surface modification of GO NPs
was performed. As shown in Figure 1, new
PEGylated products GO-PEG was synthesised via
amide bond formation after the coupling reaction of
GO and 4-arm-PEG5K-NH2 in the present of 1-ethyl3- (3-dimethylaminopropyl)carbodiimide hypochlorite
(EDC HCl).
The physiochemical properties of both GO and GOPEG were investigated using pH, zeta potential and
Nanoparticle Tracking Analysis (NTA).
3 During the
initial antifungal screening, all treated C. albicans
cultures were visualized using an ...