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dc.contributor.author | Fiuza Luces, María del Carmen | |
dc.contributor.author | Díez Bermejo, Jorge | |
dc.contributor.author | Fernández de la Torre, Miguel | |
dc.contributor.author | Rodríguez Romo, Gabriel | |
dc.contributor.author | Sanz Ayan, Paz | |
dc.contributor.author | Delmiro, Aitor | |
dc.contributor.author | Munguía-Izquierdo, Diego | |
dc.contributor.author | Rodríguez Gómez, Irene | |
dc.contributor.author | Lucía Mulas, Alejandro | |
dc.contributor.author | Morán, María | |
dc.date.accessioned | 2018-06-19T15:33:08Z | |
dc.date.available | 2018-06-19T15:33:08Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Fiuza-Luces, C., Díez-Bermejo, J., la Torre Fernández-de, M., Rodríguez-Romo, G., Sanz-Ayán, P., Delmiro, A., ... & Arenas, J. (2018). Health Benefits of an Innovative Exercise Program for Mitochondrial Disorders. Medicine and science in sports and exercise, 50(6), 1142–1151. | spa |
dc.identifier.issn | 0195-9131 | |
dc.identifier.uri | http://hdl.handle.net/11268/7308 | |
dc.description.abstract | Purpose We determined the effects of an innovative 8-wk exercise intervention (aerobic, resistance, and inspiratory muscle training) for patients with mitochondrial disease. Methods Several end points were assessed in 12 patients (19–59 yr, 4 women) at pretraining, posttraining, and after 4-wk detraining: aerobic power, muscle strength/power and maximal inspiratory pressure (main end points), ability to perform activities of daily living, body composition, quality of life, and blood myokines (secondary end points). Results The program was safe, with patients’ adherence being 94% ± 5%. A significant time effect was found for virtually all main end points (P ≤ 0.004), indicating a training improvement. Similar findings (P ≤ 0.003) were found for activities of daily living tests, total/trunk/leg lean mass, total fat mass, femoral fracture risk, and general health perception. No differences were found for blood myokines, except for an acute exertional increase in interleukin 8 at posttraining/detraining (P = 0.002) and in fatty acid binding protein 3 at detraining (P = 0.002). Conclusions An intervention including novel exercises for mitochondrial disease patients (e.g., inspiratory muscle training) produced benefits in numerous indicators of physical capacity and induced a previously unreported shift toward a healthier body composition phenotype. | spa |
dc.description.sponsorship | Sin financiación | spa |
dc.language.iso | eng | spa |
dc.subject.other | Mitochondrial disorders | spa |
dc.subject.other | Innovative exercise program | spa |
dc.title | Health Benefits of an Innovative Exercise Program for Mitochondrial Disorders | spa |
dc.type | article | spa |
dc.description.impact | 4.478 JCR (2018) Q1, 6/83 Sport Sciences | spa |
dc.description.impact | 2.071 SJR (2018) Q1, 12/289 Orthopedics and Sports Medicine, 5/209 Physical Therapy, Sports Therapy and Rehabilitation, 8/125 Sports Science | spa |
dc.description.impact | No data IDR 2018 | spa |
dc.identifier.doi | 10.1249/MSS.0000000000001546 | |
dc.rights.accessRights | closedAccess | spa |
dc.subject.uem | Ejercicio físico | spa |
dc.subject.uem | Calidad de vida | spa |
dc.subject.unesco | Beneficios complementarios | spa |
dc.subject.unesco | Deporte | spa |
dc.description.filiation | UEM | spa |
dc.peerreviewed | Si | spa |
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