Resumen:
While hepatitis C virus (HCV) infection seems
to be expanding among HIV-infected men who have sex
with men (MSM), the rate of coinfection in intravenous
drug users (IDU) is assumed to remain constant. We evaluated
the serial prevalence of HIV/HCV coinfection across
all risk groups for HIV infection in Spain. We used data
from 7045 subjects included in the multicentre, prospective
Spanish Cohort of Adult HIV-infected Patients
(CoRIS) between 2004 and 2011. We analysed risk
factors for HIV/HCV coinfection by logistic regression
analyses. The prevalence of HIV/HCV coinfection
decreased from 25.3% (95% CI, 23.1–27.5) in 2004–
2005 to 8.2% (95% CI, 6.9–9.5) in 2010–2011. This
trend was consistently observed from 2004 to 2011
among all risk groups: IDU, 92.4% to 81.4%; MSM, 4.7%
to 2.6%; heterosexual men, 13.0–8.9%; and heterosexual
women, 14.5–4.0% (all P < 0.05). Strongest risk factors
for HIV/HCV coinfection were IDU (OR, 54.9; 95% CI,
39.4–76.4), birth decade 1961–1970 (OR, 2.1; 95% CI,
1.1–3.7) and low educational level (OR, 2.4; 95%
CI, 1.6–3.5). Hence, the prevalence of HIV/HCV coinfection
decreased in Spain between 2004 and 2011. This
decline was obse...