Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy

Oliver Gil, Sandra; Giménez Alventosa, Vicent; Berumen Murillo, Francisco; Giménez Gómez, Vicent; Beaulieu, Luc; Ballester Pallarés, Facundo; Vijande Asenjo, Javier

doi:10.1016/j.zemedi.2022.11.002

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Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy

Oliver Gil, Sandra; Giménez Alventosa, Vicent; Berumen Murillo, Francisco; Giménez Gómez, Vicent; Beaulieu, Luc; Ballester Pallarés, Facundo; Vijande Asenjo, Javier

Use este identificador para citar o enlazar este ítem: http://hdl.handle.net/11268/11969

Fecha: 2023

Materia UNESCO: Cáncer
Materia UNESCO: Tratamiento médico
Materia UNESCO: Modelo de simulación

Tipo: article

Versión del editor: https://doi.org/10.1016/j.zemedi.2022.11.002

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Resumen:

The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed.

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