The multifaceted impact of circadian disruption on cancer risk: insights and economic implications

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URI: https://hdl.handle.net/11268/16238
DOI: 10.1016/j.jncc.2025.04.005

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2025

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Navarro Jiménez, Eduardo
Benítez Agudelo, Juan Camilo
Beltrán Velasco, Ana Isabel
Ramos Campo, Domingo Jesús
Villanueva- Tobaldo, Carlota Valeria

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goal-3
goal-4

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14

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Abstract

Circadian disruption has emerged as a significant risk factor for cancer, driven by mechanisms such as hormonal imbalances, impaired DNA repair, immune suppression, and metabolic dysregulation. Modern societal patterns—shift work, artificial light at night, and irregular sleep schedules—have exacerbated these risks. This study conducts a systematic review following Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, screening over 500 studies published between 2003 and 2023.

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Cáncer
Medicina preventiva
Biología molecular

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Clemente-Suarez, V. J., Navarro-Jiménez, E., Benitez-Agudelo, J. C., Beltrán-Velasco, A. I., Belinchón-deMiguel, P., Ramos-Campo, D. J., Villanueva-Tobaldo, C. V., Martín-Rodríguez, A., & Tornero-Aguilera, J. F. (2025). The multifaceted impact of circadian disruption on cancer risk: A systematic review of insights and economic implications. Journal of the National Cancer Center, S2667005425000651. https://doi.org/10.1016/j.jncc.2025.04.005
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https://doi.org/10.1016/j.jncc.2025.04.005

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journal article

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Área de Ciencias de la Salud
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