Differential inflammatory responses to acute exercise and ex vivo immune challenge in young and master athletes

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dc.contributor.authorGuerra Minuzzi, Luciele
dc.contributor.authorSouza Teixeira, Alexandre Abilio De
dc.contributor.authorFigueiredo, Caique
dc.contributor.authorDorneles, Gilson
dc.contributor.authorCastelo Branco, Anna Cláudia
dc.contributor.authorValenzuela, Pedro L.
dc.contributor.authorPeres, Alessandra
dc.contributor.authorLucía Mulas, Alejandro
dc.contributor.authorNotomi Sato, Maria
dc.contributor.authorRosa Neto, José Cesar
dc.contributor.authoret al.
dc.date.accessioned2026-07-28T14:34:31Z
dc.date.available2026-07-28T14:34:31Z
dc.date.issued2025
dc.description.abstractLifelong exercise is associated with beneficial immune adaptations, but the extent to which these adaptations manifest during an acute inflammatory challenge remains unclear. Therefore, we aimed to compare the inflammatory responses to ex vivo whole blood and peripheral blood mononuclear cells [PBMCs] cultures from young and master athletes, before and after a single bout of moderate-intensity exercise. Young athletes exhibit a stronger cytokine response to ex vivo inflammatory stimuli, while master athletes demonstrate a more controlled and regulated inflammatory profile.en
dc.description.filiationUEMspa
dc.description.impact7.0 Q1 JCR 2025
dc.description.impact1.964 Q1 SJR 2025
dc.description.impactNo data IDR 2024
dc.description.sponsorshipFinanciado por la Coordinación para el Perfeccionamiento del Personal de Educación Superior (CAPES), Brasil (código 001).es
dc.description.sponsorshipVer financiación en https://doi.org/10.3389/fimmu.2025.1601405es
dc.identifier.citationMinuzzi, L. G., De Souza Teixeira, A. A., Figueiredo, C., Dorneles, G., Branco, A. C. C., Silva, B. S. D. A., Valenzuela, P. L., Peres, A., Lucia, A., Sato, M. N., Rosa Neto, J. C., Krüger, K., & Lira, F. S. (2025). Differential inflammatory responses to acute exercise and ex vivo immune challenge in young and master athletes. Frontiers in Immunology, 16, 1601405. https://doi.org/10.3389/fimmu.2025.1601405
dc.identifier.doi10.3389/fimmu.2025.1601405
dc.identifier.issn1664-3224
dc.identifier.urihttps://hdl.handle.net/11268/17330
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.3389/fimmu.2025.1601405
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.otherCiencias del Deporte
dc.subject.otherEjercicio Físico
dc.subject.otherCitocinas
dc.subject.otherInmunidad Celular
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.unescoCiencias médicas
dc.subject.unescoInmunología
dc.subject.unescoMedicina deportiva
dc.titleDifferential inflammatory responses to acute exercise and ex vivo immune challenge in young and master athletesen
dc.typejournal article
dc.type.hasVersionVoR
dspace.entity.typePublication
relation.isAuthorOfPublicationd3691359-d7bd-4a12-b84e-338e28c81f9f
relation.isAuthorOfPublication.latestForDiscoveryd3691359-d7bd-4a12-b84e-338e28c81f9f

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