Progression of serum creatinine and glomerular filtration rate in neonatal critical care patients during the first seven days of life

Abstract

Serum creatinine and estimated glomerular filtration rate (GFR) are key indicators of kidney function. This descriptive, retrospective study included neonatal patients admitted to a tertiary hospital's neonatal intensive care unit from January 2013 to December 2016. Data on kidney function were collected from birth to 7 days of life. Patients were stratified into four gestational age groups: below 28 weeks, 28–31 weeks, 32–36 weeks, and term neonates. Qualitative variables were expressed as percentages. Quantitative variables were assessed using the Kruskal–Wallis/Wilcoxon tests. Chi-square analysis was performed for categorical variables. Statistical analysis was conducted using SPSS (Version 22.0), with significance set at p < 0.05.