Remote, lower-intensity, multidomain lifestyle intervention for subjective cognitive decline or mild cognitive impairment (APPLE-Tree): a multicentre, single-masked, randomised controlled trial
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Demnitz-King, Harriet
Adeleke, Mariam
Barber, Julie
Poppe, Michaela
Budgett, Jessica
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Trials of high-intensity, multidomain interventions show that modifying lifestyle and psychological risk factors can slow cognitive decline. We aimed to evaluate the effectiveness of a lower-intensity, personally-tailored dementia prevention programme in improving cognition in adults with subjective cognitive decline or mild cognitive impairment.
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UNESCO Subjects
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Demnitz-King, H., Adeleke, M., Barber, J. A., Poppe, M., Budgett, J., Alberts, S., Duffy, L., Minihane, A.-M., Gillings, R., Chapman, H., Espinoza Jeraldo, R. I., Kelsey, O., Muralidhar, M., Zabihi, S., Aguirre, E., Bass, N., Betz, A., Brodaty, H., Burton, A., … Cooper, C. (2025). Remote, lower-intensity, multidomain lifestyle intervention for subjective cognitive decline or mild cognitive impairment (Apple-tree): A multicentre, single-masked, randomised controlled trial. The Lancet Healthy Longevity, 6(10), 100777. https://doi.org/10.1016/j.lanhl.2025.100777






