Low-Dose Oral Minoxidil during Chemotherapy: A Review of the Mechanism and Current Evidence
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Kearney, Caitlin A.
Gordon, Allison
Markova, Alina
Freites Martínez, Azael David
Tattersall, Ian W.
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Abstract
Chemotherapy-induced alopecia (CIA) significantly impacts patients’ quality of life. While low-dose oral minoxidil (LDOM) shows promise in treating CIA after chemotherapy completion, its safety and efficacy when given during active chemotherapy remain unclear. This review examined existing literature on CIA pathogenesis, minoxidil’s mechanism of action, and LDOM efficacy to explore its potential use during chemotherapy.
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Kearney, C. A., Gordon, A., Markova, A., Freites-Martinez, A., Tattersall, I. W., Shapiro, J., Lacouture, M. E., & Lo Sicco, K. I. (2025). Low-dose oral minoxidil during chemotherapy: A review of the mechanism and current evidence. Skin Appendage Disorders, 1-9. https://doi.org/10.1159/000548112




