Disease-specific crosstalk of Alistipes with lipoprotein profiles in overweight individuals at high cardiometabolic risk

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dc.contributor.authorCuevas Sierra, Amanda
dc.contributor.authorHiguera Gómez, Andrea
dc.contributor.authorCuevillas, Begoña de
dc.contributor.authorAmigó, Núria
dc.contributor.authorMartínez Urbistondo, María
dc.contributor.authorCastejón, Raquel
dc.contributor.authorVargas, J. Antonio
dc.contributor.authorMartínez, J. Alfredo
dc.date.accessioned2026-02-27T19:13:07Z
dc.date.available2026-02-27T19:13:07Z
dc.date.issued2026
dc.description.abstractMetabolic syndrome (MS) and systemic lupus erythematosus (SLE) represent two pathophysiologically distinct chronic conditions associated with elevated cardiovascular risk. Emerging evidence links gut microbiota to host lipid metabolism and lipoprotein function. This investigation aimed to analyze disease-specific relations between gut microbiota and an advanced lipoprotein profiling in an overweight population affected by MS and SLE. The results highlight condition-specific host–microbiota–lipid relationship and supports the use of novel approaches to guide precision strategies for cardiovascular risk reduction in high-risk populations.en
dc.description.filiationUEMspa
dc.description.impact3.9 Q1 JCR 2024
dc.description.impact0.874 Q1 SJR 2024
dc.description.impactNo data IDR 2024
dc.description.sponsorshipFinanciado por “Metacategorización personalizada de los procesos inflamatorios asociados con el síndrome metabólico, las enfermedades autoinmunes y virales para la medicina de precisión” (METAINFLAMACIÓN, ref.: Y2020/BIO-6600), financiado a su vez por el Gobierno de la Comunidad de Madrid, España..es
dc.description.sponsorshipFinanciado por “Funcionalización de bigeles basados en subproductos del algarrobo para la formulación de productos cárnicos: evaluación preclínica y clínica en diabesidad” (BICAROBESITY-CM, ref. TEC-2024/BIO-307), financiado a su vez por el Gobierno de la Comunidad de Madrid, España.es
dc.identifier.citationCuevas-Sierra, A., Higuera-Gómez, A., De Cuevillas, B., Amigó, N., Martínez-Urbistondo, M., Castejón, R., Vargas, J. A., & Martínez, J. A. (2026). Disease-specific crosstalk of Alistipes with lipoprotein profiles in overweight individuals at high cardiometabolic risk. Scientific Reports. https://doi.org/10.1038/s41598-026-36024-0
dc.identifier.doi10.1038/s41598-026-36024-0
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/11268/16922
dc.language.isoeng
dc.peerreviewedSi
dc.relation.publisherversionhttps://doi.org/10.1038/s41598-026-36024-0
dc.rightsAttribution 4.0 Internationalen
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.otherFarmacia
dc.subject.otherBioquímica
dc.subject.otherLupus Eritematoso Sistémico
dc.subject.sdgGoal 3: Ensure healthy lives and promote well-being for all at all ages
dc.subject.sdgGoal 9: Build resilient infrastructure, promote sustainable industrialization and foster innovation
dc.subject.unescoCiencias médicas
dc.subject.unescoMicrobiología
dc.subject.unescoGenética
dc.titleDisease-specific crosstalk of Alistipes with lipoprotein profiles in overweight individuals at high cardiometabolic risken
dc.typejournal article
dc.type.hasVersionAM
dspace.entity.typePublication

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