Non-coding RNAs and coronary artery disease
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Cardona Monzonís, Alejandro
García Giménez, José Luis
Mena Mollá, Salvador
Guía Galipienso, Fernando de la
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Abstract
Coronary artery disease (CAD) is the leading death cause worldwide. Non-coding RNA (ncRNA) are key regulators of genetic expression and thus can affect directly or indirectly the development and progression of different diseases. ncRNA can be classified in several types depending on the length or structure, as long non-coding RNA (lncRNA), microRNA (miRNA) and circularRNA (circRNA), among others. These types of RNA are present within cells or in circulation, and for this reason they have been used as biomarkers of different diseases, therefore revolutionizing precision medicine. Recent research studied the capability of circulating ncRNA to inform about CAD presence and predict the outcome of the disease. In this chapter we present a list of the miRNA, lncRNA and circRNA which are potential biomarkers of CAD.
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Cardona-Monzonís, A., García-Giménez, J. L., Mena-Mollá, S., Pareja-Galeano, H., de la Guía-Galipienso, F., Lippi, G., Pallardó, F. V., & Sanchis-Gomar, F. (2020). Non-coding RNAs and Coronary Artery Disease. In Non-coding RNAs in Cardiovascular Diseases (pp. 273-285). Springer. https://doi.org/10.1007/978-981-15-1671-9_16