Obesity-driven alterations in adipose-derived stem cells are partially restored

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URI: http://hdl.handle.net/11268/5118
DOI: 10.1002/oby.21405

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2016

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Pérez, Laura M.
Bernal, Aurora
Suárez, Javier
San Martín, Nuria

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Abstract

The therapeutic potential of adipose-derived stem cells (ASCs) is reduced by various stress-inducing conditions that affect tissue homeostasis such as diabetes, aging, and obesity. Previous works have provided evidence of negative effects of obesity on ASC populations, but it is unclear whether this persists after a weight loss. This study evaluated whether weight loss can restore the attenuated properties found in ASCs derived from populations with obesity (oASCs).

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Obesidad
Endocrinología
Sistema endocrino

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Bibliographic reference

Pérez, L. M., Suárez, J., Bernal, A., de Lucas, B., San Martin, N., & Gálvez, B. G. (2016). Obesity‐driven alterations in adipose‐derived stem cells are partially restored by weight loss. Obesity, 24(3), 661-669.

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journal article

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Área de Biomedicina Clásica