Physical Function, Life Expectancy, and Cognitive Impairment in Older Adults: A 12-Year Longitudinal Cohort Study
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Gallardo Gómez, Daniel
Álvarez Barbosa, Francisco
Alfonso Rosa, Rosa M.
Ramos Munell, Javier
Saco Ledo, Gonzalo
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Abstract
Preventing dementia is crucial due to its current and projected global prevalence. Older adults with cognitive impairment/dementia have worse physical function than healthy individuals. However, it is important to quantify the association between performance-based physical function and life expectancy. This study aimed to assess how performance-based physical function affects life expectancy in older adults with and without mild cognitive impairment and dementia.
Maintaining good physical function in older adults is associated with increased life expectancy free of MCI or dementia, and may extend life without dementia in persons with MCI. These findings underscore the importance of promoting active aging to mitigate the burden of cognitive decline.
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Gallardo-Gómez, D., Álvarez-Barbosa, F., Alfonso Rosa, R. M., Ramos-Munell, J., Saco-Ledo, G., Chastin, S., Lucia, A., Del Pozo-Cruz, J., & Del Pozo Cruz, B. (2026). Physical function, life expectancy, and cognitive impairment in older adults: A 12-year longitudinal cohort study. Journal of the American Medical Directors Association, 27(6), 106182. https://doi.org/10.1016/j.jamda.2026.106182