Spinal mechanisms and feasibility of Dry Needling versus Botulinum Toxin Type A in poststroke lower limb spasticity: A proof-of-concept randomized clinical trial protocol (STROKE-POC)

Abstract

Stroke often causes spasticity, impacting mobility and quality of life. Botulinum Toxin type A and Dry Needling are treatments that reduce spasticity, although Botulinum Toxin type A injections can cause adverse effects. No studies have directly compared their effects at spinal, muscular, functional, quality-of-life, and cost-effectiveness levels. This study aims to determine the spinal mechanisms of BTX-A and DN on post-stroke lower limb spasticity, while also assessing feasibility, safety, and exploratory effects at muscular, functional, quality-of-life, and cost-effectiveness levels.