Differential contribution of T-type voltage-gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits
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Suárez, Andrea
Guerra Ojeda, Sol
Zarzoso, Manuel
Serna García, Marta
Vila, José Manuel
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Abstract
T-type voltage-gated calcium channels (VGCCs) are comparatively understudied in large conduit artery function relative to the well-characterized L-type channel subtype. This study investigates the vascular roles of T-type VGCCs in the aorta and renal artery of healthy rabbits using functional reactivity assays and immunofluorescence and further elucidates the interaction between T-type VGCC activity and the nitric oxide (NO) signalling pathway.
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Suarez, A., Guerra‐Ojeda, S., Zarzoso, M., Serna‐García, M., Vila, J. M., Serna, E., & Mauricio, M. D. (2025). Differential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits. Experimental Physiology, EP093044. https://doi.org/10.1113/EP093044




