Impact of natriuresis on worsening renal function during episodes of acute heart failure

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Caravaca Pérez, Pedro
Fernández Herrero, Ignacio
Broseta, José Jesús
Ibarra Márquez, Nikein
Blázquez Bermejo, Zorba

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Worsening renal function (WRF) is a frequent complication in acute heart failure (AHF) with a controversial prognostic value. We aimed to study the usefulness of natriuresis to evaluate WRF. We conducted an observational, prospective, multicenter study of patients with AHF who underwent a furosemide stress test. The patients were classified according to whether WRF was present or absent and according to the median natriuretic response. The main endpoint was the combination of mortality, rehospitalization due to HF, and heart transplant at 6 months of follow-up.

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Caravaca Pérez, P., Fernández-Herrero, I., Broseta, J. J., Ibarra-Márquez, N., Blázquez-Bermejo, Z., López-Azor, J. C., Del Castillo Gordillo, C., Cobo Marcos, M., De Juan Bagudá, J., García Cosío, M. D., García-Álvarez, A., Farrero, M., & Delgado, J. F. (2025). Impact of natriuresis on worsening renal function during episodes of acute heart failure. Revista Española de Cardiología (English Edition), 78(3), 196-205. https://doi.org/10.1016/j.rec.2024.07.006

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