Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
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Hay, Simon I.
Ong, Kanyin Liane
Santomauro, Damian F.
Bhoomadevi, A.
Aalipour, Mohammad Amin
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For more than three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has provided a framework to quantify health loss due to diseases, injuries, and associated risk factors. This paper presents GBD 2023 findings on disease and injury burden and risk-attributable health loss, offering a global audit of the state of world health to inform public health priorities. This work captures the evolving landscape of health metrics across age groups, sexes, and locations, while reflecting on the remaining post-COVID-19 challenges to achieving our collective global health ambitions.
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Hay, S. I., Ong, K. L., Santomauro, D. F., A, B., Aalipour, M. A., Aalruz, H., Ababneh, H. S., Abaraogu, U. O., Abate, B. B., Abbafati, C., Abbas, N., Abbasifard, M., Abbasi-Kangevari, M., Abd ElHafeez, S., Abdalla, A. N., Abdalla, M. A., Abdallah, E. M., Abdeeq, B. A., Abdel Razeq, N. M. I., … Gakidou, E. (2025). Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: A systematic analysis for the Global Burden of Disease Study 2023. The Lancet, 406(10513), 1873-1922. https://doi.org/10.1016/S0140-6736(25)01637-X






