Brandimonte Hernández, MarcoHernández Ruiz, ÁngelaRuiz Ojeda, Francisco JavierGil, Ángel2026-05-212026-05-212026Brandimonte-Hernández, M., Hernández-Ruiz, A., Ruiz-Ojeda, F. J., & Gil, Á. (2026). Effects of food bioactive compounds on oxidative stress and the antioxidant defense system in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials. Nutrition Reviews, nuaf292. https://doi.org/10.1093/nutrit/nuaf2920029-66431753-4887https://hdl.handle.net/11268/17115Type 2 diabetes mellitus (T2DM) is a global health problem characterized by chronic hyperglycemia, which disrupts the antioxidant defense system and increases reactive oxygen species. These changes contribute to the progression and complications of diabetes. The present study aimed to systematically review the effects of bioactive food compounds on oxidative stress and the antioxidant defense systems in patients with T2DM.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Elementos de respuesta antioxidanteDiabetes mellitus tipo 2Estrés oxidativoElementos de respuesta antioxidantejournal article10.1093/nutrit/nuaf292open accessNutriciónMedicina preventivaInvestigación médicaGoal 3: Ensure healthy lives and promote well-being for all at all ages