Oliver Gil, SandraGiménez Alventosa, VicentBerumen Murillo, FranciscoGiménez Gómez, VicentBeaulieu, LucBallester Pallarés, FacundoVijande Asenjo, Javier2023-03-292023-03-292023Oliver, S., Giménez-Alventosa, V., Berumen, F., Gimenez, V., Beaulieu, L., Ballester, F., & Vijande, J. (2023). Benchmark of the penred monte carlo framework for hdr brachytherapy. Zeitschrift Für Medizinische Physik, 33(4), 511-528. https://doi.org/10.1016/j.zemedi.2022.11.0020939-38891876-4436http://hdl.handle.net/11268/11969The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed.engBraquiterapiajournal article10.1016/j.zemedi.2022.11.002open accessCáncerTratamiento médicoModelo de simulación