Fernández Rodríguez, José MaríaAlonso Ortiz, M. B.Casado, JesúsChivite Guillén, DavidCubo Romano, PilarGarcía Alonso, R.Lorenzo Almorós, AnaMiramontes González, J.P.Soler Rangel, María LlanosPérez Silvestre, José2026-03-112026-03-112026Fernández Rodríguez, J. M., Alonso-Ortíz, M. B., Casado Cerrada, J., Chivite Guillen, D., Cubo Romano, P., García Alonso, R., Lorenzo Almorós, A., Miramontes-González, J. P., Soler Rangel, L., & Pérez-Silvestre, J. (2026). Heart failure with preserved ejection fraction: Updated diagnostic and therapeutic strategies. SEMI consensus document. Revista Clínica Española (English Edition), 226(3), 502471. https://doi.org/10.1016/j.rceng.2026.502471https://hdl.handle.net/11268/16945Heart failure (HF) is associated with high morbidity and mortality. HF with preserved left ventricular ejection fraction (HF-pEF) accounts for up to 50% of all HF cases, being the most common in elderly patients. In addition, these subjects frequently present other comorbidities. For all these reasons, the diagnosis of patients with HF-pEF is complex and requires a careful approach. In addition, there are "secondary" or HF-pEF forms that must also be discarded. The treatment of HF-pEF has evolved very significantly in recent years due to evidence from clinical trials. All this makes it necessary to update the recommendations regarding the management of patients with HF-pEF.enghttps://creativecommons.org/licenses/by-nc-nd/4.0/Insuficiencia cardiacaInhibidores del Cotransportador de Sodio-Glucosa 2Semaglutidajournal article10.1016/j.rceng.2026.502471open accessEnfermedad cardiovascularMedicina preventivaInvestigación médicaGoal 3: Ensure healthy lives and promote well-being for all at all ages