Santodomingo Rubido, JacintoVilla Collar, CésarGilmartin, BernardGutiérrez Ortega, Ángel Ramón2013-11-272013-11-272012Santodomingo-Rubido, J., Villa-Collar, C., Gilmartin, B., & Gutiérrez-Ortega, R. (2012). Orthokeratology vs. spectacles: adverse events and discontinuations. Optometry & Vision Science, 89(8), 1133-1139.10405488http://hdl.handle.net/11268/652PURPOSE: To assess the relative clinical success of orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) in children in terms of incidences of adverse events and discontinuations over a 2-year period. METHODS: Sixty-one subjects 6 to 12 years of age with myopia of - 0.75 to - 4.00DS and astigmatism ≤1.00DC were prospectively allocated OK or SV correction. Subjects were followed at 6-month intervals and advised to report to the clinic immediately should adverse events occur. Adverse events were categorized into serious, significant, and non-significant. Discontinuation was defined as cessation of lens wear for the remainder of the study. RESULTS: Thirty-one children were corrected with OK and 30 with SV. A higher incidence of adverse events was found with OK compared with SV (p < 0.001). Nine OK subjects experienced 16 adverse events (7 significant and 9 non-significant). No adverse events were found in the SV group. Most adverse events were found between 6 and 12 months of lens wear, with 11 solely attributable to OK wear. Significantly more discontinuations were found with SV in comparison with OK (p < 0.05). CONCLUSIONS: The relatively low incidence of adverse events and discontinuations with OK is conducive for the correction of myopia in children with OK contact lenses.engMyopia ControlOrthokeratologyAdverse EventsDiscontinuationsDrop OutSpectaclesRatesOvernight OrthokeratologyBerkeley OrthokeratologyContact-LensesHong-KongChildrenMyopiaSafetyEyesOphthalmologyjournal article10.1097/OPX.0b013e318263c5afrestricted accessOftalmología