Ortiz Alonso, JavierBustamante-Ara, NataliaValenzuela Ruiz, Pedro LuisVidán, María TeresaRodríguez Romo, GabrielMayordomo Cava, JenniferJavier González, MariannaHidalgo Gamarra, MercedesLucía Mulas, AlejandroSerra-Rexach, José A.Et al.2020-03-272020-03-272020Ortiz-Alonso, J., Bustamante-Ara, N., Valenzuela Ruiz, P. L., Vidán-Astiz, M., Rodríguez-Romo, G., Mayordomo-Cava, J., Javier-González, M., Hidalgo-Gamarra, M., Lopéz-Tatis, M., Valades-Malagón, M. I., Santos-Lozano, A., Lucía Mulas, A., & Serra-Rexach, J. A. (2020). Effect of a Simple Exercise Program on Hospitalization-Associated Disability in Older Patients: A Randomized Controlled Trial. Journal of the American Medical Directors Association, 21(4), 531-537, e1. https://doi.org/10.1016/j.jamda.2019.11.0271525-86101538-9375http://hdl.handle.net/11268/8873Objective Hospitalization-associated disability [HAD, ie, the loss of ability to perform ≥1 basic activities of daily living (ADLs) independently at discharge] is a frequent condition among older patients. The present study assessed whether a simple inpatient exercise program decreases HAD incidence in acutely hospitalized very old patients. Design In this randomized controlled trial (Activity in Geriatric Acute Care) participants were assigned to a control or intervention group and were assessed at baseline, admission, discharge, and 3 months thereafter. Setting and Participants In total, 268 patients (mean age 88 years, range 75–102) admitted to an acute care for older patients unit of a public hospital were randomized to a control (n = 125) or intervention (exercise) group (n = 143). Methods Both groups received usual care, and patients in the intervention group also performed simple supervised exercises (walking and rising from a chair, for a total duration of ∼20 minutes/day). We measured ADL function (Katz index) and incident HAD at discharge and after 3 months (primary outcome) and Short Physical Performance Battery, ambulatory capacity, number of falls, rehospitalization, and death during a 3-month follow-up (secondary outcomes). Results Median duration of hospitalization was 7 days (interquartile range 4 days). The intervention group had a lower risk of HAD with reference to both baseline [odds ratio (OR) 0.36; 95% confidence interval (CI) 0.17–0.76, P = .007] and admission (OR 0.29; 95% CI 0.10–0.89, P = .030). A trend toward an improved ADL function at discharge vs admission was found in the intervention group compared with controls (OR 0.32; 95% CI ‒0.04 to 0.68; P = .083). No between-group differences were noted for the other endpoints (all P > .05).engjournal article10.1016/j.jamda.2019.11.027restricted accessAncianosHospitalizadosEjercicio físicoAncianoHospitalDeporte