Sanz Santiago, VerónicaDíez Vega, IgnacioSantana Sosa, ElenaLópez Nuevo, Carlos EnriqueIturriaga Ramírez, TamaraVendrusculo, Fernanda MaríaDonadio, Márcio Vinícius FagundesVilla Asensi, José RamónPérez Ruiz, Margarita2020-10-292020-10-292020Sanz, V., Díez, I., Santana, E., López, C., Iturriaga, T., Vendrusculo, F. M., ... & Pérez, M. (2020). Effect of a combined exercise program on physical fitness, lung function, and quality of life in patients with controlled asthma and exercise symptoms: A randomized controlled trial. Pediatric Pulmonology, 55(7), 1608-1616. https://doi.org/10.1002/ppul.247988755-68631099-0496http://hdl.handle.net/11268/9246Background Asthmatic patients may benefit from exercise training, although the effects of a combined aerobic and resistance training program are still poorly investigated in children and adolescents. Objective To analyze the effects of a combined exercise training (resistance and aerobic) program on aerobic fitness, lung function, asthma control and quality of life in a group of mild‐moderate asthmatic children with exercise symptoms. Methods This was a 12‐week randomized controlled trial including children and adolescents diagnosed with mild‐moderate asthma and presenting exercise‐induced symptoms. The intervention group (IG) performed the exercise training (resistance and aerobic) 3 days/week, for 60 minutes. The control group (CG) followed routine clinical orientations. The main outcomes were cardiorespiratory fitness, muscle strength, lung function, quality of life, asthma control, and functional tests after 3 months of the intervention. Results Fifty‐three patients (IG = 25 and CG = 28) with a mean age of 11.5 ± 2.6 years were included. No significant differences were found between groups regarding lung function, asthma control, quality of life, and functional tests. Ventilatory equivalent for oxygen consumption at ventilatory threshold (P = .025; = 0.083), peak oxygen consumption (P = .008; = 0.116) and test duration (P = .014; = 0.1) presented greater improvements in the IG. In addition, improvements were observed in leg press (P < .001; = 0.36), hamstring curl (P = .001; = 0.217), high row (P = .003; = .167), low row (P = .009; = 0.128) and quadriceps leg extension (P = .015; = 0.108) in the IG. Conclusion Combined exercise training (resistance and aerobic) improved cardiorespiratory fitness and muscle strength in children and adolescents with controlled asthma and exercise symptoms.engjournal article10.1002/ppul.24798embargoed accessAsma en niñosFisiología del ejercicioMedicina deportivaEfectos fisiológicosMedicina deportivaEnfermedad