Eynon, NirBanting, Lauren K.Cieszczyk, PawelDyatlov, D. A.Maciejewska-Karlowska, AgnieszkaSawczuk, MarekPushkarev, Vladimir P.Kulikov, L. M.Pushkarev, E.D.Femia Marzo, PedroStepto, N.K.Bishop, David J.Lucía Mulas, Alejandro2014-04-212014-04-212014Eynon, N., Banting, L. K., Ruiz, J. R., Cieszczyk, P., Dyatlov, D. A., Maciejewska-Karlowska, A., ..., & Lucía-Mulas, A. (2014). ACTN3 R577X polymorphism and team-sport performance: a study involving three European cohorts. Journal of Science and Medicine in Sport, 17(1), 102-106.14402440http://hdl.handle.net/11268/2763OBJECTIVES: To determine the association between the α-actinin-3 (ACTN3) R577X polymorphism and elite team-sport athletic status in three cohorts of European team-sport athletes. DESIGN: We compared the genotype and allele frequencies of the ACTN3 R577X (rs1815739) polymorphisms between team-sport athletes (n=205), endurance athletes (n=305), sprint/power athletes (n=378), and non-athletic controls (n=568) from Poland, Russia and Spain; all participants were unrelated European men. RESULTS: Team-sport athletes were less likely to have the 577RR genotype compared to the 577XX genotype than sprint/power athletes [odds ratio: 0.58, 95% confidence interval: 0.34-0.39, p=0.045]. However, the ACTN3 R577X polymorphism was not associated with team-sports athletic status, compared to endurance athletes and non-athletic controls. CONCLUSIONS: The ACTN3 R577X polymorphism was not associated with team-sport athletic status.engjournal article10.1016/j.jsams.2013.02.005restricted accessGenéticaCiencias de la vida