Clemente Suárez, Vicente JavierMartín Rodríguez, AlexandraYáñez Sepúlveda, RodrigoTornero Aguilera, José Francisco2023-07-272023-07-272023Clemente-Suárez, V. J., Martín-Rodríguez, A., Yáñez-Sepúlveda, R., & Tornero-Aguilera, J. F. (2023). Mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment. International Journal of Molecular Sciences, 24(10), 8848. https://doi.org/10.3390/ijms241088481661-65961422-0067http://hdl.handle.net/11268/12223Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of mitochondria from one cell to another, has recently emerged as a potential therapeutic approach for restoring mitochondrial function in diseased cells. In this review, we summarize the current understanding of mitochondrial transfer, including its mechanisms, potential therapeutic applications, and impact on cell death pathways. We also discuss the future directions and challenges in the field of mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment.engAttribution 4.0 International (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/Terapia de reemplazo mitocondrialMuerte celularNeoplasiasjournal article10.3390/ijms24108848open accessEnfermedad del sistema nerviosoEnfermedad nutricionalMedicina preventiva