Genchi, FabioBlaya Tárraga, Juan AntonioPalma Carrió, CristinaEstévez Llorens, RaquelMenéndez Nieto, Isabel2026-02-132026-02-132026Genchi, F., Blaya Tárraga, J. A., Palma Carrió, C., Estévez Llorens, R., & Menéndez Nieto, I. (2026). Hemostatic agents in periapical surgery: Systematic review and meta-analysis. Journal of Endodontics, S0099239926000373. https://doi.org/10.1016/j.joen.2026.02.0040099-23991878-3554https://hdl.handle.net/11268/16816The purpose of this systematic review with meta-analysis was to analyze the hemostatic efficacy in periapical surgery and their influence on the prognosis. A secondary objective was to study the influence of clinical variables both patient- and tooth-related. A systematic review protocol was developed following the PRISMA guidelines. A comprehensive search was carried out in PubMed, Scopus, Web of Science and Cochrane Library up to October 2024. Inclusion criteria were randomized controlled trials (RCTs) and controlled clinical trials (CCTs) analyzing the efficacy of hemostatic agents in periapical surgery and their relationship with treatment prognosis.engHemostasisHemostáticosApicectomíajournal article10.1016/j.joen.2026.02.004embargoed accessOdontologíaMedicina preventivaInvestigación médicaGoal 3: Ensure healthy lives and promote well-being for all at all ages