Díez Delhoyo, FelipeValero Masa, María JesúsVelásquez Rodríguez, JesúsDevesa Cordero, CarolinaSousa Casasnovas, IagoJuárez Fernández, MiriamAngulo Llanos, RocíoFernández Fernández-Avilés, FranciscoMartínez Sellés Oliveria Soares, Manuel2017-01-052017-01-052017Díez-Delhoyo, F., Valero-Masa, M. J., Velásquez-Rodríguez, J., Devesa-Cordero, C., Sousa-Casasnovas, I., Juárez, M., ... & Martínez-Sellés, M. (2017). Very low risk ST-segment elevation myocardial infarction? It exists and may be easily identified. International Journal of Cardiology, 228, 615-620. DOI: 10.1016/j.ijcard.2016.11.27601675273http://hdl.handle.net/11268/6136Early discharge protocols have been proposed for ST-segment elevation myocardial infarction (STEMI) low risk patients despite the existence of few but significant cardiovascular events during mid-term follow-up. We aimed to identify a subgroup of patients among those considered low-risk in which prognosis would be particularly good. We analyzed 30-day outcomes and long-term follow-up among 1.111 STEMI patients treated with reperfusion therapy. Multivariate analysis identified seven variables as predictors of 30-day outcomes: Femoral approach; age > 65; systolic dysfunction; postprocedural TIMI flow < 3; elevated creatinine level > 1.5 mg/dL; stenosis of left-main coronary artery; and two or higher Killip class (FASTEST). A total of 228 patients (20.5%), defined as very low-risk (VLR), had none of these variables on admission. VLR group of patients compared to non-VLR patients had lower in-hospital (0% vs. 5.9%; p < 0.001) and 30-day mortality (0% vs. 6.25%: p < 0.001). They also presented fewer in-hospital complications (6.6% vs. 39.7%; p < 0.001) and 30-day major adverse events (0.9% vs. 4.5%; p = 0.01). Significant mortality differences during a mean follow-up of 23.8 ± 19.4 months were also observed (2.2% vs. 15.2%; p < 0.001). The first VLR subject died 11 months after hospital discharge. No cardiovascular deaths were identified in this subgroup of patients during follow-up. About a fifth of STEMI patients have VLR and can be easily identified. They have an excellent prognosis suggesting that 24–48 h in-hospital stay could be a feasible alternative in these patients.engjournal article10.1016/j.ijcard.2016.11.276restricted accessInfarto de miocardioCardiopatía coronariaEnfermedad cardiovascularSistema cardiovascular