Mota, Jhulia Caroline Nunes Leal daSmaira, Fabiana I.Gualano, BrunoCruz Mosso, Ulises De laCampos López, BerthaMora García, Paulina E.Pesqueda Cendejas, KarenHiguera Gómez, AndreaCuevas Sierra, AmandaMartínez, J. Alfredoet al.2026-09-032026-09-032026Da Mota, J. C., Smaira, F. I., Gualano, B., Mosso, U. D. L. C., Campos-López, B., Mora-García, P. E., Pesqueda-Cendejas, K., Meza, M. R. M., Vizmanos, B., Higuera-Gómez, A., De Cuevillas, B., Cuevas-Sierra, A., Martínez-Urbistondo, M., Martinez, J. A., & Nicoletti, C. F. (2026). Association between fat-free mass, lipid profile and cardiovascular risk indices in women with systemic lupus erythematosus: A multicenter cross-sectional study. Nutrition, 151, 113333. https://doi.org/10.1016/j.nut.2026.1133330899-90071873-1244https://hdl.handle.net/11268/17399Women with systemic lupus erythematosus (SLE) exhibit increased cardiovascular risk, partly explained by adverse fat distribution. This multicenter cross-sectional study investigated whether fat-free mass (FFM) is independently related to lipid metabolism and cardiovascular risk and identified metabolic clusters combining body composition and lipid parameters in women with SLE from an Ibero-American cohort. In women with SLE, greater fat-free mass was associated with a more favorable lipid profile and selected atherogenic indices, independent of demographic and disease-related factors. Although causality cannot be inferred due to the cross-sectional design, these findings suggest that lean mass may represent an important component of cardiometabolic health in SLE.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Farmacia y nutriciónLupus Eritematoso SistémicoDislipidemiasEnfermedades Cardiovascularesjournal article10.1016/j.nut.2026.113333open accessCiencias médicasMedicina clínicaNutriciónGoal 3: Ensure healthy lives and promote well-being for all at all ages