Bustamante-Ara, NataliaSantiago Dorrego, CatalinaVerde Rello, ZoraidaYvert, Thomas PaulGómez Gallego, FélixRodríguez Romo, GabrielGonzález Gil, PedroSerra-Rexach, José A.Ruiz, Jonatan R.Lucía Mulas, Alejandro2013-11-272013-11-272010Bustamante-Ara, N., Santiago-Dorrego, C., Verde-Rello, Z., Yvert, T., Gómez-Gallego, F., Rodríguez-Romo, G., ..., & Lucía-Mulas, A. (2010). ACE and ACTN3 genes and muscle phenotypes in nonagenarians. International Journal of Sports Medicine, 31(4), 221-224.14393964http://hdl.handle.net/11268/259We studied the association of ACE and ACTN3 polymorphisms with skeletal muscle phenotypes (i. e. upper and lower body muscular strength and functional tests) in Spanish nonagenarian subjects [n=41, 33 women, 8 men, age: 90-97 years]. Mean values of the study phenotypes were not significantly different (all P>0.05) between ACE and ACTN3 genotypes. The analyses of the combined effects between genotypes ( ACE DD & ACTN3 RR/RX vs. ACE II/ID & ACTN3 XX) did not yield any significant difference. Our data suggest that, in the elderly, the influence of genetic factors on muscle phenotype traits is not reducible to a few single polymorphisms, including ACE and ACTN3 variants.engjournal article10.1055/s-0030-1247529restricted accessGenética humana